Oooo well, pretty as that is, that's a long render time...
I find when working with clouds that the 'quality' slider will creep up above 1 while I'm not looking. Maybe check yours haven't gone crazy high on the quality settings. Another suggestion is to go through all your fractal nodes, turn off all displacement on nodes you don't need displacement on, and increase minimum size on anything that's really small. Eg a minimum scale of 0.01m is not going to be seen from space, so that can go much much higher.