Ok, just had to try it. Rendered with detail .8
Row 1 is rendered with High population quality.
Row 2 Column 1 has a second render at High to use as a control.
Row 2 Column 2 is rendered with the Highest population quality.
Row 3 is Row 2 set to difference over Row 1.
I'll have to try this with a lower detail setting to see if the difference is greater. I don't see too many instances where I would use the highest setting, but to each their own.