General relativity (GR) and quantum mechanics (QM) are both ultra tested in their domains and, at the same time, are completely at odds each other so there MUST be something amiss somewhere.
Recently there were news about the work of Erik Verlinde about gravity being an emergent phenomena
http://www.physicsforums.com/showthread.php?t=373815 and not something fundamental.
My personal bet is that our perception of reality is quite different from what reality is (assuming that there IS something we can call reality) and the fight between GR and QM is due to the fact that while QM describes something fundamental, GR is a second order approximation of emergent phenomena.
Anyway, current and near future experiments are entering the sensibility region in which we will be able to detect useful discrepancies.
In addition, the possible range of masses for the Higgs boson is being trimmed down almost every day and I really hope that in the end we will find that it does not exists, because in this case the Standard Model is not the end of the story but an approximation of supersymmetric ones.
Bye!!!
