Cyphyr, me too! I run Vista Home Premium 64 bit on i7 940 cpu with NVIDIA GeForce GTX 295. When I run TG2, other background programs start going crazy on me. I get lots of errors including the ones that you mention. If my machine wasn't so stable running other applications, I'd suspect hardware, but rather I'm suspecting that the multi-core feature of TG2 has a memory leak. I can't prove it, but I suspect it. Vista is probably letting TG2 have system memory that it isn't locking down.