I must be very lucky. My typical workflow is I put up a second full screen preview on my second monitor with shaders, atmosphere, and lighting active. Plus objects as wireframe. I do pause the small preview but soometimes let it render when my secondary preview is in a different view, usually top. I can't remember a crash since I've started using TG3, except when I cause it by poking around in the settings while a render is active, which is of course, not recommneded.
Maybe it's because I running that old OS winXP!
The below image is my setup with the exception the full preview is usually on the second monitor.